An empty intramammary syringe is an unfilled packaging and delivery component intended for veterinary pharmaceutical filling projects. It is commonly selected for products developed for intramammary administration, including mastitis products, dry cow therapy formulations and teat sealant products.

Unlike a finished veterinary medicine, an empty intramammary syringe does not contain an active pharmaceutical ingredient or a completed drug formulation. It is supplied to veterinary pharmaceutical manufacturers, animal health brands, contract filling companies and distributors for subsequent filling, assembly and packaging.

Selecting the appropriate syringe therefore involves more than choosing a nominal volume. Capacity, formulation viscosity, plunger movement, applicator-tip design, cap closure, filling compatibility and secondary packaging can all affect the final project.

Why Intramammary Product Development Is Receiving More Attention

Intramammary products remain an important part of dairy animal health management. The European Medicines Agency revised its guideline on efficacy studies for intramammary products used in cattle; Revision 3 came into effect on September 1, 2025. The guideline covers products administered through the teat canal for clinical and subclinical mastitis, treatment at drying off and prevention of new intramammary infections during the dry period.

In a CVMP assessment report dated March 12, 2026, the EMA reviewed quarter-based selective dry cow therapy. The broader referral conclusion states that selective approaches can help reduce antimicrobial use when supported by appropriate herd management, accurate diagnostics and the use of teat sealants.

These regulatory and animal health discussions relate to veterinary medicinal products rather than empty packaging. However, they demonstrate that intramammary products are developed for different treatment, prevention and dry-period management strategies.

For packaging buyers, this means that an empty intramammary syringe should be assessed according to the intended formulation and filling process rather than treated as a single standard container for every application.

What Is an Empty Intramammary Syringe?

An empty intramammary syringe is a plastic syringe tube supplied without medicine for use in veterinary pharmaceutical production.

· A syringe barrel

· A plunger

· A cap

· An applicator tip or nozzle configuration

· Printed or labelled product identification

· Individual or bulk packaging

The exact component structure can vary according to the filling process, intended product, user handling requirements and desired presentation.

The syringe manufacturer supplies the packaging components, while the veterinary pharmaceutical company or its contract filling partner is responsible for the formulation, filling, regulatory approval and final medicinal product.

Empty Intramammary Syringe

Key Factors When Selecting an Empty Intramammary Syringe

1. Select a Capacity That Matches the Filling Volume

Intramammary products are not all filled at the same volume. The selected syringe should provide sufficient capacity for the intended formulation while allowing for filling accuracy, closure and normal production tolerances.

Xinfuda currently lists the following reference capacities for its PE intramammary syringe range:

· 5ml

· 8ml

· 10ml

· 13ml

The most appropriate capacity should be confirmed according to the actual filling volume and product design rather than selected only according to the maximum nominal volume.

2. Evaluate the Formulation’s Physical Properties

Intramammary formulations can differ in viscosity and flow behaviour. A relatively fluid formulation may perform differently from a dense paste or teat sealant material.

Packaging evaluation may therefore include:

· Required plunger force

· Smoothness of plunger movement

· Barrel and plunger fit

· Residual product after dispensing

· Leakage resistance

· Tip opening and flow characteristics

· Closure performance during transportation and storage

A syringe that performs well with one formulation may not automatically be suitable for another. Sample filling and dispensing tests should be completed using the buyer’s actual formulation whenever possible.

3. Match the Applicator Tip to the Intended Application

The applicator tip is one of the most important structural elements of an intramammary syringe.

Its design can influence:

· Product dispensing

· User handling

· Cap attachment

· Protection before use

· Final product positioning

· Compatibility with the intended administration procedure

Dry cow therapy products, mastitis products and teat sealant products may require different considerations. The tip and nozzle should therefore be discussed during the packaging-development stage rather than selected only after the syringe barrel has been confirmed.

Packaging suppliers should not independently determine the clinical administration method. The final tip design and instructions for use must be evaluated by the veterinary medicine developer in accordance with the intended product and applicable regulatory requirements.

4. Review Cap Closure and Sealing

The cap helps protect the syringe opening before the final product is used. Its fit and closure should be evaluated as part of the complete packaging system.

Important points can include:

· Cap retention

· Ease of assembly

· Protection of the tip

· Resistance to accidental opening

· Compatibility with the filling and capping process

· Performance during storage and transportation

For formulations with higher viscosity, cap and nozzle design may require particular attention because product contact with the tip area can affect the final closure process.

5. Confirm Compatibility With the Filling Process

Veterinary pharmaceutical companies and contract fillers should evaluate how the empty syringe will be supplied and introduced into production.

Questions to discuss with the packaging supplier include:

· Will the components be filled manually, semi-automatically or automatically?

· Should the barrel, plunger and cap be supplied separately?

· What orientation is required for filling?

· How will the cap be installed?

· Is individual packaging required?

· Is bulk packaging more appropriate for the production line?

· What sample quantity is needed for a filling trial?

Packaging that is convenient for a small pilot batch may need a different supply arrangement when the project moves to commercial production.

6. Consider Printing and Brand Identification

An empty intramammary syringe can also form part of the finished product’s visual identity.

Depending on the project, customization can include:

· Barrel color

· Cap color

· Plunger color

· Printing on the barrel

· Label area

· Product identification

· Individual packaging

· Export carton design

Printing and color decisions should remain subordinate to functional requirements. A visually distinctive syringe still needs to perform consistently during filling, closure, transportation and dispensing.

Empty Intramammary Syringes for Teat Sealant Projects

Teat sealant formulations can present particular packaging challenges because of their physical consistency and dispensing requirements.

For a teat sealant syringe project, buyers may need to evaluate:

· Formulation viscosity

· Syringe capacity

· Plunger force

· Tip dimensions

· Nozzle opening

· Cap design

· Filling method

· Leakage and transportation performance

The EMA’s selective dry cow therapy review identified teat sealants as one element that can support selective approaches when combined with good herd management and accurate diagnostics. This does not establish a packaging specification, but it highlights the continuing relevance of teat sealant products in modern dry-period management.

The packaging configuration must still be validated by the product developer for the specific formulation.

Why Sample Confirmation Is Important

A catalogue specification can help buyers identify a preliminary option, but it cannot replace product-specific testing.

Before bulk production, the veterinary pharmaceutical company or filling partner should consider testing:

· Actual filling volume

· Formulation compatibility

· Plunger movement

· Dispensing consistency

· Tip performance

· Cap closure

· Printing adhesion

· Packaging configuration

· Transportation conditions

Sample testing is particularly important when the formulation is highly viscous, when a special applicator tip is required or when the syringe will be used on an automated filling line.

Xinfuda Empty Intramammary Syringe Options

Xinfuda supplies empty intramammary syringe tubes for veterinary pharmaceutical production and filling projects.

The current product range includes PE syringe references in:

· 5ml

· 8ml

· 10ml

· 13ml

The standard reference products consist of a barrel, plunger and cap. Project-specific requirements involving the applicator tip, nozzle design, capacity, barrel color, cap, plunger, printing, individual packaging and bulk packaging can be discussed during product development.

The syringes are supplied as empty packaging components. They do not contain veterinary medicine or active pharmaceutical ingredients.

Xinfuda can support:

· Veterinary pharmaceutical companies

· Dairy animal health brands

· Contract filling factories

· Veterinary product distributors

· OEM animal health packaging projects

· Mastitis product packaging

· Dry cow tube projects

· Teat sealant syringe projects

Sample confirmation is recommended before commercial production.

Related Veterinary Packaging Solutions

Buyers developing a broader animal health packaging portfolio can also review Xinfuda’s veterinary syringe solutions for prefilled packaging formats used with oral gels, creams and nutritional pastes.

For multi-dose oral formulations, the company also supplies dosing paste syringes in multiple reference sizes for horse, cattle and pet product projects.

Veterinary Syringe Set

Frequently Asked Questions

What is an empty intramammary syringe?

An empty intramammary syringe is an unfilled veterinary packaging and delivery component intended to be filled with an approved intramammary formulation by a veterinary pharmaceutical manufacturer or contract filling company.

Does an empty intramammary syringe contain medicine?

No. An empty intramammary syringe is supplied without medicine or active pharmaceutical ingredients.

What sizes of empty intramammary syringes does Xinfuda offer?

Xinfuda lists reference capacities of 5ml, 8ml, 10ml and 13ml.

What material is used for Xinfuda intramammary syringes?

The listed Xinfuda intramammary syringe references are made from PE.

Can an empty intramammary syringe be used for teat sealant packaging?

An intramammary syringe can be developed for a teat sealant packaging project, subject to evaluation of the capacity, formulation viscosity, plunger, applicator tip, nozzle and cap requirements.

Can the applicator tip be customized?

Applicator-tip and nozzle requirements can be discussed according to the product application, filling process and user-handling requirements.

Are bulk empty intramammary syringes available?

Bulk packaging can be discussed for veterinary pharmaceutical filling projects. The component arrangement and packaging method should be confirmed according to the buyer’s production process.

Should samples be tested before placing a bulk order?

Yes. Sample confirmation and formulation-specific filling tests are recommended before bulk production.

Discuss Your Intramammary Syringe Packaging Project

Choosing an empty intramammary syringe requires coordination between the veterinary medicine developer, filling company and packaging supplier.

Provide the following information when requesting a quotation:

· Required filling volume

· Formulation type and approximate viscosity

· Intended product application

· Preferred syringe capacity

· Tip or nozzle requirements

· Cap requirements

· Printing and color requirements

· Individual or bulk packaging preference

· Filling method

· Estimated order quantity

Xinfuda can provide samples and discuss an appropriate empty intramammary syringe configuration for mastitis products, dry cow therapy products and teat sealant packaging projects.