In the veterinary pharmaceutical industry, the choice of packaging is paramount for ensuring drug stability, safe transport, and ease of administration. Prefilled syringes, which combine the functions of a "primary container" and a "syringe" into a single unit, have emerged as a preferred solution. Their advantages, including precise dosing, user convenience, reduced risk of contamination, and minimized product waste, are driving adoption. However, a critical challenge for veterinary companies is selecting packaging that guarantees leak-proof performance and maintains seal integrity to preserve drug efficacy.

The sealing performance of a prefilled syringe is the cornerstone of its functionality. Currently, there are no specific international industry standards for veterinary prefilled syringes. Therefore, when sourcing these devices, manufacturers must verify that their suppliers adhere to widely recognized standards. These include the Chinese Veterinary Drug Packaging Standard YBB00112004-2015 and the international ISO 11040 series. These standards set rigorous requirements for all components, especially the critical sealing elements like the piston. Choosing a syringe with compliant sealing components is the fundamental step toward ensuring integrity.

Beyond the standards for components, the precise interaction between the piston and the plunger rod is another vital factor affecting seal quality. Veterinary companies can employ specialized tests to validate this compatibility. One common method involves connecting the plunger to the piston, inserting them into a silicone-lubricated syringe barrel half-filled with water, expelling air, and then testing the plunger's movement for smoothness and stability. This simple test can reveal potential issues that might lead to leakage in a multidose syringe or a dial a dose syringe over time.

To ensure the syringe maintains its seal throughout the drug's shelf life, comprehensive testing beyond routine checks is essential. This includes stress tests, accelerated aging studies, and stability testing that simulate various environmental conditions. These validations assess the long-term durability and stability of the syringe's seal. Furthermore, seal integrity must be verified against bacterial ingress test requirements and saturated salt solution tests to guarantee the drug remains uncontaminated during storage and use.

For specialized applications like administering viscous formulations, the demand for integrity is even higher. A paste syringe or a precise dosing syringe for paste must withstand higher pressures without compromising the seal. Any failure can lead to inaccurate dosing and product spoilage, directly impacting animal health and treatment outcomes.

The seal integrity of a prefilled syringe is not just a technical specification; it directly influences a veterinary company's brand reputation and market competitiveness. A leaky syringe can lead to product recalls, financial losses, and a loss of trust. Therefore, a meticulous approach to selection—focusing on component standards, piston/plunger compatibility, and rigorous multi-stage testing—is non-negotiable. By prioritizing these factors, veterinary pharmaceutical companies can secure reliable, high-performance packaging that ensures drug safety and efficacy, laying a solid foundation for sustainable growth and excellence in animal healthcare.

About Xinfuda Pharmaceutical Packaging Co., Ltd.:

We are a leading provider of advanced packaging solutions for the veterinary industry, specializing in high-quality prefilled syringes designed to meet the highest standards of seal integrity and performance.

veterinary pre-filled syringes