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Determination of transmittance of pharmaceutical packaging

Carrie Dec 13,2019 Share this post:

The light transmittance of a pharmaceutical packaging refers to the ratio of the luminous flux transmitted through the sample to the luminous flux incident on the sample, expressed as a percentage. For light-sensitive pharmaceutical preparations, pharmaceutical packaging materials need to provide good light-shielding properties for the preparations; for high-risk pharmaceutical preparations such as injections, the pharmaceutical packaging materials must achieve a certain light transmission performance so that the status of the content drugs can be observed with the naked eye. This method is suitable for measuring the light transmittance of glass containers and plastic containers and materials.


COP vials


Light transmission method

Unless otherwise specified, flat pieces of appropriate size are cut from different parts of the test product, placed in a colorimetric cell in a direction perpendicular to the incident light, filled with water, and using water as a blank and 450 nm as Measure the wavelength and record the transmittance of the test article.

Notes

1. The size of the test product is recommended to cover the entrance window of the integrating sphere. If the test item is too small to completely cover the entrance window, use opaque paper or tape to cover the uncovered part of the entrance window.

2. The glass container can be cut with a circular saw equipped with a wet grinding wheel. The grinding wheel can be made of diamond or diamond.

3. The test product should be placed properly so that the light beam is perpendicular to the surface of the test product with minimal loss of reflection.

4. The surface of the test product should be smooth and clean to prevent scratches and fingerprints.


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