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HDPE bottle USP standard differential thermal scanning method

Carrie Apr 01,2019 Share this post:

The HDPE bottle USP standard is compared with the national standard mainly by the infrared spectrum detection method and heavy metal detection. Among them, the USP quality standard mid-infrared spectrum is mainly detected by differential scanning calorimetry.

Differential scanning calorimetry,DSC, is a way of thermal analysis.


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The difference in power (eg, in the form of heat) input to the sample and reference is measured at program-controlled temperature versus temperature. The curve recorded by the differential scanning calorimeter is called the DSC curve, which is the rate of endothermic or exothermic heat of the sample, ie the heat flow rate dH/dt (units of millijoules per second) is plotted on the ordinate, and the temperature T or time t is horizontal. Coordinates can measure a variety of thermodynamic and kinetic parameters such as specific heat capacity, heat of reaction, heat of transition, phase diagram, reaction rate, crystallization rate, polymer crystallinity, sample purity, and the like. The method has a wide temperature range (-175~725 °C), high resolution, and low sample consumption. Suitable for inorganic, organic compounds and pharmaceutical analysis.


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HDPE bottle USP standard differential calorimetry is an analytical method for measuring the energy difference between a sample and a reference with temperature under temperature-programmed conditions. Differential scanning calorimetry has both compensation and heat flow. In differential scanning calorimetry, the relationship between the amount of heat and temperature that must be applied per unit time in order to keep the temperature difference between the sample and the reference at zero is the DSC curve. The vertical axis of the curve is the amount of heating per unit time, and the horizontal axis is temperature or time. The area of the curve is proportional to the change in enthalpy. DSC has the same principle as DTA, but its performance is better than DTA. The measured heat is more accurate than DTA, and the resolution and reproducibility are better than DTA. It can be used to study biofilm structure and function, protein and nucleic acid conformational changes.

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